Crusader Against Seed Oil
04/07/2024 (Sun) 00:53
Id: f4ab60
No.227237
del
>>227236No bongs for me!
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One of the most abundant and cytotoxic lipid-derived aldehyde is 4-hydroxy 2-nonenal (HNE). The HNE is formed by the oxidation of ω-6 polyunsaturated fatty acids [5; Figure-1].
During autoxidation, fatty acids form alkoxyl radicals [6] that undergo beta-scission leading to the formation of several saturated and unsaturated oxo-compounds of which HNE is one of the most reactive and under some conditions represents 95% of the generated aldehydes [7].
Currently, HNE is considered an important marker of oxidative stress, a possible contributory agent to several diseases such as Alzheimer and a stimulant of prominent pathobiochemical pathways such as inflammation, indicating a potential contribution of the aldehyde to the pathogenesis of several chronic diseases [8–10].
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